Before injection
Find the right tissue
Spot healthy tissue to use and damaged tissue to avoid, and track site health over time.
Diabetes technology · In development
A handheld scanner and app designed to help people who inject insulin find healthy tissue, avoid damaged sites and rotate with confidence.
The problem
of people who inject insulin develop lipohypertrophy, a buildup of damaged fatty tissue under the skin.1
of insulin pump users in one study had it when their sites were checked by ultrasound.2
consumer products let people check the health of their own injection and infusion sites today.
Infusion-site problems have been called “the Achilles heel” of insulin pump therapy.3
1. Blanco M, et al. Diabetes & Metabolism, 2013. 2. Study of lipohypertrophy in insulin pump users, PMC8803446. 3. Heinemann L, Krinelke L. J Diabetes Sci Technol, 2012.
The product
Glide Loci over the area you're about to use. It's designed to read the tissue underneath in seconds and show a simple light: green to go, yellow for caution, red to avoid. Try it: pick a zone, then move the scanner over it.
Illustrative demo of the intended experience. Detection performance is not yet clinically validated.
Loci checks tissue before an injection, and is being designed to check absorption after.
Before injection
Spot healthy tissue to use and damaged tissue to avoid, and track site health over time.
After injection · Planned add-on
Scan beside your infusion set to see whether insulin is absorbing slowly, too fast or not at all, so you can change a failing set early.
How it works
Place the scanner on the site you plan to use. One hand, one device. No gel and no patches.
The indicator is designed to show whether the tissue looks healthy, borderline or damaged, right on the device.
Inject or place your set. The app logs the site, builds your personal map and suggests where to go next.
Designed for daily life
The app
Illustrative concept. Viability maps require clinical validation.
Who it's for
A bad site can lock you in for two to three days. Loci helps you choose a good one the first time.
Pens and syringes too. Stop returning to the same familiar spots.
GLP-1s, fertility treatment, growth hormone and more. Anyone who injects regularly could benefit from healthier sites.
We also work with clinicians, diabetes educators and device makers who want fewer failed sites and better outcomes for the people they serve.
US planning estimates based on published prevalence, pump-use and prescription data. Uses beyond insulin are future possibilities and would require their own evidence.
Built with the community
conversations with people with diabetes, nurses, endocrinologists and pump-industry leaders
concern raised by the people with diabetes we interviewed: anxiety about infusion sets
average likelihood to adopt, from five type 1 users who handled our early design prototype
Loci customer discovery interviews, 2026. Early, small samples; not a clinical study.
Our path
Loci is a medical device, and we're building it like one: bench validation, then a clinical accuracy study against ultrasound, then FDA review.
Handheld form factor and user experience, reviewed with people who live with type 1 diabetes. US provisional patent filed.
Integrating the sensing electronics and testing the signal in the lab against tissue models and confounders like pressure and movement.
Comparing Loci's readings with ultrasound at real injection and infusion sites, under IRB oversight.
A planned 510(k) submission, to be confirmed with FDA through a pre-submission meeting.
Founders
Two of our three founders live with type 1 diabetes and have spent years managing their own injection and infusion sites. Together, we're building the tool they wish they'd had.

Co-founder & CEO
Diabetes research at UCSF, biotech finance, and a Berkeley MBA / M.Eng.
Lives with type 1 diabetes
Co-founder & Chief Brand Officer
Industrial designer from Loughborough University who designed the Loci prototype.
Lives with type 1 diabetes
Co-founder & CTO
Medical device engineer with a UC Davis M.Eng., leading sensing and electronics.
We're expanding our team and advisors across engineering, clinical research and regulatory. If you want to work on a problem millions of people live with every day, we'd love to hear from you.
Not yet. Loci is in development and has not been cleared by the FDA. Join the waitlist and we'll let you know about early access and research studies.
Loci is designed to work alongside what you already use: pens, syringes, tubed pumps and tubeless pods. It doesn't connect to or control your pump.
Loci is designed to be painless: you simply place the scanner on your skin. No needles, no gel and no patches.
No. Loci is a small handheld device that lives in your diabetes kit and comes out when you need it.
Damaged tissue is often hard to see or feel, especially early. Loci is being designed to help find it before it affects your insulin, and to show where healthy tissue is.
Join the waitlist and choose how you'd describe yourself. We're especially interested in hearing from pump users, clinicians and diabetes educators who'd like to take part in research.
Early access
Join the waitlist for early access, study opportunities and product updates. Clinicians, investors and partners, we'd love to hear from you too.
Or email hello@locimedical.com